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12.7% of Americans who are 13 or older take antidepressant medication on a monthly basis.

Antidepressants could lead to lifelong dependence, doctors warn, since going off them can trigger agitation, headaches, and flu-like symptoms

Antidepressants aren't known to be addictive like other prescription pills, but going off them can lead to unpleasant physical effects.

Brain scans could be used to identify who will benefit from antidepressants

A new study by Stanford University looked at the brain activity of 309 people to find out who would benefit from sertraline, a generic of Zoloft.
Being honest with your partner about what you're dealing with could do wonders for your sex life.

My antidepressants make it difficult to orgasm. How do I tell my partner and make sex fun again?

Before switching medications, take time to explore your own body, talk with your partner, and try some bedroom problem-solving.
Illustration photo shows various medicine pills in their original packaging in Brussels

Sage Therapeutics craters 64% after failing a key trial for its depression drug

The Cambridge-based drugmaker posted promising trial results for the key antidepressant earlier this year.
Antidepressants work by affecting neurotransmitters.

How antidepressants work, according to a psychiatrist

Depression affects millions of Americans and antidepressants are relatively common. We talked to a psychiatrist to find out how they work.

Regulators just approved a new depression drug with the potential to be a game-changer

Unlike the depression drugs available for decades, neither of the two new drugs is a pill. One is a nasal spray; the latest is an injection made by Sage.

A drug that works differently from all existing depression drugs just got a big boost

Sage's new antidepressant may be called a "blockbuster" for good reason: it appears to be the first to differ significantly from 35 years worth of treatments.

A fresh crop of promising drugs is poised to change the way depression is treated for the first time in decades. Here are the ones to watch in 2019.

Researchers are on the hunt for better drugs to treat depression, a leading cause of disability worldwide. Promising options include ketamine and psilocybin.

A ‘party drug’ with potential to be the next blockbuster antidepressant is edging closer to the mainstream, but it could set you back $9,0...

Once dismissed as a "party drug," ketamine is emerging as a potential alternative treatment for depression.
23andMe Co-Founder and CEO Anne Wojcicki

Regulators just gave DNA-testing startup 23andMe the go-ahead to offer a health product that scientists have called dubious

23andMe CEO Anne Wojcicki had said she hoped the company would bring back a test designed to help customers choose a medication based on their DNA.